About Us

Carbometrics Ltd. was founded in 2018 following the acquisition of Ziylo Ltd by Novo Nordisk. Our core competency is the design, synthesis, and derivatisation of highly selective and robust synthetic Glucose Binding Molecules. Ziylo was acquired to support Novo Nordisk’s strategic goal to develop the world’s first glucose-responsive insulins and transform the treatment of diabetes.

Two scientists in lab coats and safety goggles discussing equipment inside a glass enclosure in a laboratory.

Ziylo’s synthetic glucose binding molecules (GBMs) were initially discovered by Professor Anthony Davis, a world-leader in the field of molecularly engineered sugar receptors based at the University of Bristol. Carbometrics negotiated an exclusive license to the non-therapeutic applications of the GBMs for uses such as CGM.

Discover more about our partnerships and services here.

A scientist working in a laboratory fume hood with glassware and scientific equipment.
Scientists working in a laboratory, wearing white lab coats, with equipment and chemicals on the benches.

state-of-the-art 200 m² synthetic organic chemistry laboratory

Carbometrics operates from a state-of-the-art 200 m² synthetic organic chemistry laboratory and office space at the Science Creates incubator site in St Philips, Bristol. The laboratories are equipped with BS EN 14175 Certified Fume Extraction and the necessary equipment to conduct sub-mg to >100 g scale chemical synthesis. “This organic synthesis capability is supported by a fully equipped analytical suite including High Performance Liquid Chromatography – Mass Spectrometry (HPLC-MS), preparative HPLC, Size-Exclusion Chromatography and Nuclear Magnetic Resonance (NMR).

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